Membran på gula fläcken - S:t Eriks Ögonsjukhus

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Myocyt (glatt muskulatur) 9. Afferent arteriol 10. Glomerulus kapillärer 11. Efferent arteriol In this video, we discuss the mechanisms of the macula densa cells in regulating GFR and blood pressure. MACULA DENSA In the kidney, the macula densa is an area of closely packed specialized cells lining the wall of the cortical thick ascending limb of the loop of Henle, at the transition to the distal convoluted tubule. The cells of the macula densa are sensitive to the concentration of sodium chloride in the late thick ascending limb. macula densa: [ mak´u-lah ] ( L. ) 1.

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Renin - tryck i afferent arteriol. - Na/Cl- i macula densa-celler. - sympatikus och beta1. +/-. ACE hämmare/AT1-blockare. Vad gör de cellerna?

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Ved stimulation kan disse celler secernere enzymet renin. 5a.

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Macula densa, 8. Myocyter (glattmuskel), 9. Avgörande arteriole, 10. Glomerulus kapillärer, 11. Efferent arteriole.

Often used alone to refer to the macula retinae. 2. a discolored spot on the skin that is not raised above the surface; called also macule .
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5a. Mesangial cell – Intraglomerulär cell 5b. Mesangial cell – Extraglomerulär cell 6.

COX-1 finns  av D Lindholm · 2018 — Intill macula densa finns anpassade glatta muskelceller, juxtaglomerulära celler. De fungerar som barosensorer och reagerar alltså på blodtryck, i den afferenta  Dessa ökar återupptaget av Na, vilket gör tubulicellerna mer positiva inuti och driver därmed ut K i urinen.
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Juxtaglomerulär apparat Svensk MeSH

Macula densa cells serve an important function in coupling renal hemodynamics with tubular reabsorption in that they monitor the sodium chloride concentration of the tubular fluid and via paracrine signaling molecules like prostaglandin E2 (PGE2), ATP, adenosine, and NO provide a feedback mechanism that adapts glomerular filtration to tubular reabsorption (tubuloglomerular William J. Arendshorst, Elsa Bello-Reuss, in Handbook of Cell Signaling (Second Edition), 2010. Macula-Densa Control of Renin Release. The macula densa participates in the regulation of renin release from juxtaglomerular granular cells. Renin secretion depends on NaCl delivery to and reabsorption by the macula-densa cells at the end of the TAL. 2021-03-12 · NEW & NOTEWORTHY This study illuminated a physiologically regulated dense network of basal cell major and minor processes (maculapodia) in macula densa (MD) cells.